Phospholipid metabolic adaptation promotes survival of IDH2 mutant acute myeloid leukemia cells
Phospholipid metabolic adaptation promotes survival of IDH2 mutant acute myeloid leukemia cells
About this item
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Publisher
England: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
England: John Wiley & Sons, Inc
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Scope and Contents
Contents
Genetic mutations in the isocitrate dehydrogenase (IDH) gene that result in a pathological enzymatic activity to produce oncometabolite have been detected in acute myeloid leukemia (AML) patients. While specific inhibitors that target mutant IDH enzymes and normalize intracellular oncometabolite level have been developed, refractoriness and resista...
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Full title
Phospholipid metabolic adaptation promotes survival of IDH2 mutant acute myeloid leukemia cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10823289
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10823289
Other Identifiers
ISSN
1347-9032,1349-7006
E-ISSN
1349-7006
DOI
10.1111/cas.15994
