Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo
Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Enhancers control gene expression and have crucial roles in development and homeostasis
1
–
3
. However, the targeted de novo design of enhancers with tissue-specific activities has remained challenging. Here we combine deep learning and transfer learning to design tissue-specific enhancers for five tissues in the
Drosophila melanoga...
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Full title
Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10830412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10830412
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-023-06905-9
