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Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains

Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10838224

Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains

About this item

Full title

Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Acta neuropathologica, 2024-06, Vol.147 (1), p.29, Article 29

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

The aggregation, mislocalization, and phosphorylation of TDP-43 are pathologic hallmarks of several neurodegenerative diseases and provide a defining criterion for the neuropathologic diagnosis of Limbic-predominant Age-related TDP-43 Encephalopathy (LATE). LATE neuropathologic changes (LATE-NC) are often comorbid with other neurodegenerative patho...

Alternative Titles

Full title

Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10838224

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10838224

Other Identifiers

ISSN

0001-6322,1432-0533

E-ISSN

1432-0533

DOI

10.1007/s00401-023-02671-0

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