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Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolat...

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolat...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843339

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia

About this item

Full title

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia

Publisher

Canada: CMA Impact Inc

Journal title

Journal of psychiatry & neuroscience, 2024-01, Vol.49 (1), p.E35-E44

Language

English

Formats

Publication information

Publisher

Canada: CMA Impact Inc

More information

Scope and Contents

Contents

ABSTRACTBackgroundSusceptibility to schizophrenia is determined by interactions between genes and environment, possibly via epigenetic mechanisms. Schizophrenia has been associated with a restrictive epigenome, and histone deacetylase (HDAC) inhibitors have been postulated as coadjuvant agents to potentiate the efficacy of current antipsychotic dru...

Alternative Titles

Full title

Permissive epigenetic regulatory mechanisms at the histone level are enhanced in postmortem dorsolateral prefrontal cortex of individuals with schizophrenia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843339

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843339

Other Identifiers

ISSN

1180-4882,1488-2434

E-ISSN

1488-2434

DOI

10.1503/jpn.230054

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