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Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843982

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

About this item

Full title

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cell and tissue research, 2017-06, Vol.368 (3), p.487-501

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Chromogranin A (CgA) is a prohormone and a granulogenic factor that regulates secretory pathways in neuroendocrine tissues. In β-cells of the endocrine pancreas, CgA is a major cargo in insulin secretory vesicles. The impact of CgA deficiency on the formation and exocytosis of insulin vesicles is yet to be investigated. In addition, no literature e...

Alternative Titles

Full title

Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843982

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10843982

Other Identifiers

ISSN

0302-766X

E-ISSN

1432-0878

DOI

10.1007/s00441-017-2580-5

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