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Accelerating the discovery of alkyl halide-derived natural products using halide depletion

Accelerating the discovery of alkyl halide-derived natural products using halide depletion

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10849952

Accelerating the discovery of alkyl halide-derived natural products using halide depletion

About this item

Full title

Accelerating the discovery of alkyl halide-derived natural products using halide depletion

Publisher

London: Nature Publishing Group UK

Journal title

Nature chemistry, 2024-02, Vol.16 (2), p.173-182

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Even in the genomic era, microbial natural product discovery workflows can be laborious and limited in their ability to target molecules with specific structural features. Here we leverage an understanding of biosynthesis to develop a workflow that targets the discovery of alkyl halide-derived natural products by depleting halide anions, a key bios...

Alternative Titles

Full title

Accelerating the discovery of alkyl halide-derived natural products using halide depletion

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10849952

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10849952

Other Identifiers

ISSN

1755-4330

E-ISSN

1755-4349

DOI

10.1038/s41557-023-01390-z

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