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Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10859687

Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

About this item

Full title

Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

Publisher

England: Oxford University Press

Journal title

Briefings in bioinformatics, 2024-01, Vol.25 (2)

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Hyperactive ribosome biogenesis (RiboSis) fuels unrestricted cell proliferation, whereas genomic hallmarks and therapeutic targets of RiboSis in cancers remain elusive, and efficient approaches to quantify RiboSis activity are still limited. Here, we have established an in silico approach to conveniently score RiboSis activity based on...

Alternative Titles

Full title

Genomic hallmarks and therapeutic targets of ribosome biogenesis in cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10859687

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10859687

Other Identifiers

ISSN

1467-5463

E-ISSN

1477-4054

DOI

10.1093/bib/bbae023

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