SIRT6 deficiency causes ovarian hypoplasia by affecting Plod1‐related collagen formation
SIRT6 deficiency causes ovarian hypoplasia by affecting Plod1‐related collagen formation
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Author / Creator
Li, Liyuan , Hua, Rui , Hu, Kaiqiang , Chen, Huiling , Yin, Yuemiao , Shi, Xiaojin , Peng, Kezheng , Huang, Qing , Qiu, Ying , Li, Xue , Liu, Qingfei , Liu, Shangfeng and Wang, Zhao
Publisher
England: John Wiley & Sons, Inc
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Language
English
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Publisher
England: John Wiley & Sons, Inc
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Contents
SIRT6 is a key member of the mammalian sirtuin family of conserved nicotinamide adenine dinucleotide (NAD+)‐dependent deacetylases. Previous studies have shown that SIRT6 can regulate metabolism, DNA damage repair and aging. Ovarian aging process usually share similar mechanisms with general aging, which is characterized by decreases in both number...
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Full title
SIRT6 deficiency causes ovarian hypoplasia by affecting Plod1‐related collagen formation
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10861214
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10861214
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ISSN
1474-9718,1474-9726
E-ISSN
1474-9726
DOI
10.1111/acel.14031