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Mrc1 + macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell prolifer...

Mrc1 + macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell prolifer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10879870

Mrc1 + macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell proliferation via the AKT/Rb signaling pathway

About this item

Full title

Mrc1 + macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell proliferation via the AKT/Rb signaling pathway

Publisher

Australia: Ivyspring International Publisher

Journal title

Theranostics, 2024-01, Vol.14 (4), p.1764-1780

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher

Subjects

Subjects and topics

More information

Scope and Contents

Contents

The present understanding of the cellular characteristics and communications in crystal nephropathy is limited. Here, molecular and cellular studies combined with single-cell RNA sequencing (scRNA-seq) were performed to investigate the changes in cell components and their interactions in glyoxylate-induced crystallized kidneys to provide promising...

Alternative Titles

Full title

Mrc1 + macrophage-derived IGF1 mitigates crystal nephropathy by promoting renal tubule cell proliferation via the AKT/Rb signaling pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10879870

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10879870

Other Identifiers

ISSN

1838-7640

E-ISSN

1838-7640

DOI

10.7150/thno.89174

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