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HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor

HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881386

HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor

About this item

Full title

HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2024-02, Vol.626 (8000), p.843-851

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

HIV-1 infection requires nuclear entry of the viral genome. Previous evidence suggests that this entry proceeds through nuclear pore complexes (NPCs), with the 120 × 60 nm capsid squeezing through an approximately 60-nm-wide central channel
1
and crossing the permeability barrier of the NPC. This barrier can be described as an FG phase
2

Alternative Titles

Full title

HIV-1 capsids enter the FG phase of nuclear pores like a transport receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881386

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10881386

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-023-06966-w

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