Mechanisms of action and resistance in histone methylation-targeted therapy
Mechanisms of action and resistance in histone methylation-targeted therapy
About this item
Full title
Author / Creator
Yamagishi, Makoto , Kuze, Yuta , Kobayashi, Seiichiro , Nakashima, Makoto , Morishima, Satoko , Kawamata, Toyotaka , Makiyama, Junya , Suzuki, Kako , Seki, Masahide , Abe, Kazumi , Imamura, Kiyomi , Watanabe, Eri , Tsuchiya, Kazumi , Yasumatsu, Isao , Takayama, Gensuke , Hizukuri, Yoshiyuki , Ito, Kazumi , Taira, Yukihiro , Nannya, Yasuhito , Tojo, Arinobu , Watanabe, Toshiki , Tsutsumi, Shinji , Suzuki, Yutaka and Uchimaru, Kaoru
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Epigenomes enable the rectification of disordered cancer gene expression, thereby providing new targets for pharmacological interventions. The clinical utility of targeting histone H3 lysine trimethylation (H3K27me3) as an epigenetic hallmark has been demonstrated
1
–
7
. However, in actual therapeutic settings, the mechanism by which H...
Alternative Titles
Full title
Mechanisms of action and resistance in histone methylation-targeted therapy
Authors, Artists and Contributors
Author / Creator
Kuze, Yuta
Kobayashi, Seiichiro
Nakashima, Makoto
Morishima, Satoko
Kawamata, Toyotaka
Makiyama, Junya
Suzuki, Kako
Seki, Masahide
Abe, Kazumi
Imamura, Kiyomi
Watanabe, Eri
Tsuchiya, Kazumi
Yasumatsu, Isao
Takayama, Gensuke
Hizukuri, Yoshiyuki
Ito, Kazumi
Taira, Yukihiro
Nannya, Yasuhito
Tojo, Arinobu
Watanabe, Toshiki
Tsutsumi, Shinji
Suzuki, Yutaka
Uchimaru, Kaoru
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10917674
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10917674
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-024-07103-x
