Targeted Suicide Gene Therapy with Retroviral Replicating Vectors for Experimental Canine Cancers
Targeted Suicide Gene Therapy with Retroviral Replicating Vectors for Experimental Canine Cancers
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Publisher
Switzerland: MDPI AG
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Language
English
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Publisher
Switzerland: MDPI AG
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Contents
Cancer in dogs has increased in recent years and is a leading cause of death. We have developed a retroviral replicating vector (RRV) that specifically targets cancer cells for infection and replication. RRV carrying a suicide gene induced synchronized killing of cancer cells when administered with a prodrug after infection. In this study, we evalu...
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Full title
Targeted Suicide Gene Therapy with Retroviral Replicating Vectors for Experimental Canine Cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10932112
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10932112
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25052657
