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The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to ab...

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to ab...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10933265

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

About this item

Full title

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

Publisher

China: Springer Nature B.V

Journal title

Bone research, 2024-03, Vol.12 (1), p.17-17

Language

English

Formats

Publication information

Publisher

China: Springer Nature B.V

More information

Scope and Contents

Contents

While hypoxic signaling has been shown to play a role in many cellular processes, its role in metabolism-linked extracellular matrix (ECM) organization and downstream processes of cell fate after musculoskeletal injury remains to be determined. Heterotopic ossification (HO) is a debilitating condition where abnormal bone formation occurs within ext...

Alternative Titles

Full title

The HIF-1α/PLOD2 axis integrates extracellular matrix organization and cell metabolism leading to aberrant musculoskeletal repair

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10933265

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10933265

Other Identifiers

ISSN

2095-4700

E-ISSN

2095-6231

DOI

10.1038/s41413-024-00320-0

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