B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
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Author / Creator
Afzali, Ali Maisam , Nirschl, Lucy , Sie, Christopher , Pfaller, Monika , Ulianov, Oleksii , Hassler, Tobias , Federle, Christine , Petrozziello, Elisabetta , Kalluri, Sudhakar Reddy , Chen, Hsin Hsiang , Tyystjärvi, Sofia , Muschaweckh, Andreas , Lammens, Katja , Delbridge, Claire , Büttner, Andreas , Steiger, Katja , Seyhan, Gönül , Ottersen, Ole Petter , Öllinger, Rupert , Rad, Roland , Jarosch, Sebastian , Straub, Adrian , Mühlbauer, Anton , Grassmann, Simon , Hemmer, Bernhard , Böttcher, Jan P. , Wagner, Ingrid , Kreutzfeldt, Mario , Merkler, Doron , Pardàs, Irene Bonafonte , Schmidt Supprian, Marc , Buchholz, Veit R. , Heink, Sylvia , Busch, Dirk H. , Klein, Ludger and Korn, Thomas
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Neuromyelitis optica is a paradigmatic autoimmune disease of the central nervous system, in which the water-channel protein AQP4 is the target antigen
1
. The immunopathology in neuromyelitis optica is largely driven by autoantibodies to AQP4
2
. However, the T cell response that is required for the generation of these anti-AQP4 antibod...
Alternative Titles
Full title
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
Authors, Artists and Contributors
Author / Creator
Nirschl, Lucy
Sie, Christopher
Pfaller, Monika
Ulianov, Oleksii
Hassler, Tobias
Federle, Christine
Petrozziello, Elisabetta
Kalluri, Sudhakar Reddy
Chen, Hsin Hsiang
Tyystjärvi, Sofia
Muschaweckh, Andreas
Lammens, Katja
Delbridge, Claire
Büttner, Andreas
Steiger, Katja
Seyhan, Gönül
Ottersen, Ole Petter
Öllinger, Rupert
Rad, Roland
Jarosch, Sebastian
Straub, Adrian
Mühlbauer, Anton
Grassmann, Simon
Hemmer, Bernhard
Böttcher, Jan P.
Wagner, Ingrid
Kreutzfeldt, Mario
Merkler, Doron
Pardàs, Irene Bonafonte
Schmidt Supprian, Marc
Buchholz, Veit R.
Heink, Sylvia
Busch, Dirk H.
Klein, Ludger
Korn, Thomas
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10937377
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10937377
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-024-07079-8
