Trimetazidine Improves Mitochondrial Dysfunction in SOD1G93A Cellular Models of Amyotrophic Lateral...
Trimetazidine Improves Mitochondrial Dysfunction in SOD1G93A Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation
About this item
Full title
Author / Creator
Salvatori, Illari , Nesci, Valentina , Spalloni, Alida , Marabitti, Veronica , Muzzi, Maurizio , Zenuni, Henri , Scaricamazza, Silvia , Rosina, Marco , Fenili, Gianmarco , Goglia, Mariangela , Boffa, Laura , Massa, Roberto , Moreno, Sandra , Mercuri, Nicola Biagio , Nazio, Francesca , Longone, Patrizia , Ferri, Alberto and Valle, Cristiana
Publisher
Basel: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Basel: MDPI AG
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More information
Scope and Contents
Contents
Amyotrophic Lateral Sclerosis (ALS) is considered the prototype of motor neuron disease, characterized by motor neuron loss and muscle waste. A well-established pathogenic hallmark of ALS is mitochondrial failure, leading to bioenergetic deficits. So far, pharmacological interventions for the disease have proven ineffective. Trimetazidine (TMZ) is...
Alternative Titles
Full title
Trimetazidine Improves Mitochondrial Dysfunction in SOD1G93A Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation
Authors, Artists and Contributors
Author / Creator
Nesci, Valentina
Spalloni, Alida
Marabitti, Veronica
Muzzi, Maurizio
Zenuni, Henri
Scaricamazza, Silvia
Rosina, Marco
Fenili, Gianmarco
Goglia, Mariangela
Boffa, Laura
Massa, Roberto
Moreno, Sandra
Mercuri, Nicola Biagio
Nazio, Francesca
Longone, Patrizia
Ferri, Alberto
Valle, Cristiana
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10970050
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10970050
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25063251
