OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ releas...
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
About this item
Full title
Author / Creator
Tsvilovskyy, Volodymyr , Ottenheijm, Roger , Kriebs, Ulrich , Schütz, Aline , Diakopoulos, Kalliope Nina , Jha, Archana , Bildl, Wolfgang , Wirth, Angela , Böck, Julia , Jaślan, Dawid , Ferro, Irene , Taberner, Francisco J , Kalinina, Olga , Hildebrand, Staffan , Wissenbach, Ulrich , Weissgerber, Petra , Vogt, Dominik , Eberhagen, Carola , Mannebach, Stefanie , Berlin, Michael , Kuryshev, Vladimir , Schumacher, Dagmar , Philippaert, Koenraad , Camacho-Londoño, Juan E , Mathar, Ilka , Dieterich, Christoph , Klugbauer, Norbert , Biel, Martin , Wahl-Schott, Christian , Lipp, Peter , Flockerzi, Veit , Zischka, Hans , Algül, Hana , Lechner, Stefan G , Lesina, Marina , Grimm, Christian , Fakler, Bernd , Schulte, Uwe , Muallem, Shmuel and Freichel, Marc
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Regulated exocytosis is initiated by increased Ca2+ concentrations in close spatial proximity to secretory granules, which is effectively prevented when the cell is at rest. Here we showed that exocytosis of zymogen granules in acinar cells was driven by Ca2+ directly released from acidic Ca2+ stores including secretory granules through NAADP-activ...
Alternative Titles
Full title
OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage
Authors, Artists and Contributors
Author / Creator
Ottenheijm, Roger
Kriebs, Ulrich
Schütz, Aline
Diakopoulos, Kalliope Nina
Jha, Archana
Bildl, Wolfgang
Wirth, Angela
Böck, Julia
Jaślan, Dawid
Ferro, Irene
Taberner, Francisco J
Kalinina, Olga
Hildebrand, Staffan
Wissenbach, Ulrich
Weissgerber, Petra
Vogt, Dominik
Eberhagen, Carola
Mannebach, Stefanie
Berlin, Michael
Kuryshev, Vladimir
Schumacher, Dagmar
Philippaert, Koenraad
Camacho-Londoño, Juan E
Mathar, Ilka
Dieterich, Christoph
Klugbauer, Norbert
Biel, Martin
Wahl-Schott, Christian
Lipp, Peter
Flockerzi, Veit
Zischka, Hans
Algül, Hana
Lechner, Stefan G
Lesina, Marina
Grimm, Christian
Fakler, Bernd
Schulte, Uwe
Muallem, Shmuel
Freichel, Marc
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10977991
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10977991
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI169428
