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Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10991561

Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

About this item

Full title

Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2023-06, Vol.72 (6), p.1633-1646

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

CD105 (endoglin) is a transmembrane protein that functions as a TGF-beta coreceptor and is highly expressed on endothelial cells. Unsurprisingly, preclinical and clinical evidence strongly suggests that CD105 is an important contributor to tumor angiogenesis and tumor progression. Emerging evidence suggests that CD105 is also expressed by tumor cel...

Alternative Titles

Full title

Tumoral CD105 promotes immunosuppression, metastasis, and angiogenesis in renal cell carcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10991561

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10991561

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-022-03356-5

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