Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorecta...
Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer
About this item
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Author / Creator
Kaneta, Akinao , Nakajima, Shotaro , Okayama, Hirokazu , Matsumoto, Takuro , Saito, Katsuharu , Kikuchi, Tomohiro , Endo, Eisei , Ito, Misato , Mimura, Kosaku , Kanke, Yasuyuki , Saito, Motonobu , Saze, Zenichiro , Fujita, Shotaro , Sakamoto, Wataru , Onozawa, Hisashi , Momma, Tomoyuki , Ohki, Shinji and Kono, Koji
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Deficient mismatch repair (dMMR)/microsatellite instability (MSI) colorectal cancer (CRC) has high immunogenicity and better prognosis compared with proficient MMR (pMMR)/microsatellite stable (MSS) CRC. Although the activation of the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway has been considered to contribute to...
Alternative Titles
Full title
Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10992387
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10992387
Other Identifiers
ISSN
0340-7004
E-ISSN
1432-0851
DOI
10.1007/s00262-022-03200-w
