Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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US: Oxford University Press
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English
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US: Oxford University Press
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Abstract
Klotho plays a critical role in the regulation of ion and fluid homeostasis. A previous study reported that haplo-insufficiency of Klotho in mice results in increased aldosterone synthase (CYP11B2) expression, elevated plasma aldosterone, and high blood pressure. This phenotype was presumed to be the result of diminished Klotho expressi...
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Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11002783
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11002783
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ISSN
1945-7170,0013-7227
E-ISSN
1945-7170
DOI
10.1210/endocr/bqae040
