Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2...
Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder
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Author / Creator
Phalnikar, Kruttika , Srividya, M , Mythri, S V , Vasavi, N S , Ganguly, Archisha , Kumar, Aparajita , S, Padmaja , Kalia, Kishan , Mishra, Srishti S , Dhanya, Sreeja Kumari , Paul, Pradip , Holla, Bharath , Ganesh, Suhas , Reddy, Puli Chandramouli , Sud, Reeteka , Viswanath, Biju and Muralidharan, Bhavana
Publisher
England: Oxford University Press
Journal title
Language
English
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Publisher
England: Oxford University Press
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Scope and Contents
Contents
Bipolar disorder (BD) is a severe mental illness that can result from neurodevelopmental aberrations, particularly in familial BD, which may include causative genetic variants. In the present study, we derived cortical organoids from BD patients and healthy (control) individuals from a clinically dense family in the Indian population. Our data reve...
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Full title
Altered neuroepithelial morphogenesis and migration defects in iPSC-derived cerebral organoids and 2D neural stem cells in familial bipolar disorder
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11024480
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11024480
Other Identifiers
ISSN
2753-149X
E-ISSN
2753-149X
DOI
10.1093/oons/kvae007
