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TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11028074

TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

About this item

Full title

TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer Immunology, Immunotherapy, 2019-01, Vol.68 (1), p.33-43

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

In recent years, immune cells were shown to play critical roles in tumor growth and metastatic progression. In this context, neutrophils were shown to possess both pro- and anti-tumor properties. To exert their anti-tumor effect, neutrophils need to migrate towards, and form physical contact with tumor cells. Neutrophils secrete H
2
O
2

Alternative Titles

Full title

TRPM2 modulates neutrophil attraction to murine tumor cells by regulating CXCL2 expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11028074

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11028074

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851

DOI

10.1007/s00262-018-2249-2

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