Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity
Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity
About this item
Full title
Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Neuropilin-1 (NRP-1)-expressing macrophages are engaged in antitumor immune functions via various mechanisms. In this study, we investigated the role of NRP-1 on macrophages in antibody-mediated tumoricidal activity. Treatment of macrophages with NRP-1 knockdown or an anti-NRP-1-neutralizing antibody significantly suppressed antibody-dependent cell...
Alternative Titles
Full title
Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11029735
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11029735
Other Identifiers
ISSN
0340-7004,1432-0851
E-ISSN
1432-0851
DOI
10.1007/s00262-017-2002-2
