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The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypepti...

The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypepti...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11030181

The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients

About this item

Full title

The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients

Publisher

Berlin: Springer

Journal title

Cancer Immunology, Immunotherapy, 2006-10, Vol.55 (10), p.1247-1257

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

Prothymosin alpha (proTalpha) is a 109 amino acid long polypeptide presenting distinct immunoenhancing activity in vitro and in vivo. Recent reports suggest that in apoptotic cells, proTalpha is cleaved by caspases at its carboxy(C)-terminus generating potentially bioactive fragments. In this study, we identified the peptide segment of proTalpha pr...

Alternative Titles

Full title

The immunologically active site of prothymosin α is located at the carboxy-terminus of the polypeptide. Evaluation of its in vitro effects in cancer patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11030181

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11030181

Other Identifiers

ISSN

0340-7004

E-ISSN

1432-0851,1365-2567

DOI

10.1007/s00262-005-0108-4

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