Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons
Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons
About this item
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Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
BACKGROUND
Impairment of the ubiquitin‐proteasome system (UPS) has been implicated in abnormal protein accumulation in Alzheimer's disease. It remains unclear if genetic variation affects the intrinsic properties of neurons that render some individuals more vulnerable to UPS impairment.
METHODS
Induced pluripotent stem cell (iPSC)‐derived...
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Full title
Person‐specific differences in ubiquitin‐proteasome mediated proteostasis in human neurons
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11032531
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11032531
Other Identifiers
ISSN
1552-5260,1552-5279
E-ISSN
1552-5279
DOI
10.1002/alz.13680
