TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation
TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation
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United States: American Society for Clinical Investigation
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Language
English
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United States: American Society for Clinical Investigation
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In lung, thromboxane A2 (TXA2) activates the TP receptor to induce proinflammatory and bronchoconstrictor effects. Thus, TP receptor antagonists and TXA2 synthase inhibitors have been tested as potential asthma therapeutics in humans. Th9 cells play key roles in asthma and regulate the lung immune response to allergens. Herein, we found that TXA2 r...
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Full title
TXA2 attenuates allergic lung inflammation through regulation of Th2, Th9, and Treg differentiation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11060738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11060738
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI165689
