Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related n...
Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Contents
Amyloid assemblies of Tau are associated with Alzheimer’s disease (AD). In AD Tau undergoes several abnormal post-translational modifications, including hyperphosphorylation and glycosylation, which impact disease progression.
N-
glycosylated Tau was reported to be found in AD brain tissues but not in healthy counterparts. This is surprising...
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Full title
Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072875
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072875
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ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-020-03643-3