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Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related n...

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related n...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072875

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration

About this item

Full title

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2021-03, Vol.78 (5), p.2231-2245

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Amyloid assemblies of Tau are associated with Alzheimer’s disease (AD). In AD Tau undergoes several abnormal post-translational modifications, including hyperphosphorylation and glycosylation, which impact disease progression.
N-
glycosylated Tau was reported to be found in AD brain tissues but not in healthy counterparts. This is surprising...

Alternative Titles

Full title

Differential effects of putative N-glycosylation sites in human Tau on Alzheimer’s disease-related neurodegeneration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072875

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11072875

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-020-03643-3

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