DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK...
DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex
About this item
Full title
Author / Creator
Zhang, Yanwei , Cen, Jing , Yuan, Gaoliang , Jia, Zhao , Chen, Kangyong , Gao, Wa , Chen, Jing , Adamek, Mikolaj , Jia, Zhiying and Zou, Jun
Publisher
Cham: Springer International Publishing
Journal title
Language
English
Formats
Publication information
Publisher
Cham: Springer International Publishing
Subjects
More information
Scope and Contents
Contents
DExD/H-box helicase (DDX) 5 belongs to the DExD/H-box helicase family. DDX family members play differential roles in the regulation of innate antiviral immune response. However, whether DDX5 is involved in antiviral immunity remains unclear. In this study, we found that DDX5 serves as a negative regulator of type I interferon (IFN) response. Overex...
Alternative Titles
Full title
DDX5 inhibits type I IFN production by promoting degradation of TBK1 and disrupting formation of TBK1 − TRAF3 complex
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11073175
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11073175
Other Identifiers
ISSN
1420-682X,1420-9071
E-ISSN
1420-9071
DOI
10.1007/s00018-023-04860-2
