Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive lon...
Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts
About this item
Full title
Author / Creator
Harding, Jeffrey , Vintersten-Nagy, Kristina , Yang, Huijuan , Tang, Jean Kit , Shutova, Maria , Jong, Eric D. , Lee, Ju Hee , Massumi, Mohammad , Oussenko, Tatiana , Izadifar, Zohreh , Zhang, Puzheng , Rogers, Ian M. , Wheeler, Michael B. , Lye, Stephen J. , Sung, Hoon-Ki , Li, ChengJin , Izadifar, Mohammad and Nagy, Andras
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The immunogenicity of transplanted allogeneic cells and tissues is a major hurdle to the advancement of cell therapies. Here we show that the overexpression of eight immunomodulatory transgenes (
Pdl1
,
Cd200
,
Cd47
,
H2-M3
,
Fasl
,
Serpinb9
,
Ccl21
and
Mfge8
) in mouse embryonic stem cells (mESCs) is...
Alternative Titles
Full title
Immune-privileged tissues formed from immunologically cloaked mouse embryonic stem cells survive long term in allogeneic hosts
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11087263
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11087263
Other Identifiers
ISSN
2157-846X
E-ISSN
2157-846X
DOI
10.1038/s41551-023-01133-y
