Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ag...
Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ageing
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Publisher
England: Nature Publishing Group UK
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Language
English
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Publisher
England: Nature Publishing Group UK
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Scope and Contents
Contents
Mitochondrial genomes co-evolve with the nuclear genome over evolutionary timescales and are shaped by selection in the female germline. Here we investigate how mismatching between nuclear and mitochondrial ancestry impacts the somatic evolution of the mitochondrial genome in different tissues throughout ageing. We used ultrasensitive duplex sequen...
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Full title
Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ageing
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11090800
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11090800
Other Identifiers
E-ISSN
2397-334X
DOI
10.1038/s41559-024-02338-3
