LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes
LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes
About this item
Full title
Author / Creator
Ding, Jingzhong , Nguyen, Anh Tram , Lohman, Kurt , Hensley, Michael T , Parker, Daniel , Hou, Li , Taylor, Jackson , Voora, Deepak , Sawyer, Janet K , Boudyguina, Elena , Bancks, Michael P , Bertoni, Alain , Pankow, James S , Rotter, Jerome I , Goodarzi, Mark O , Tracy, Russell P , Murdoch, David M , Rich, Stephen S , Psaty, Bruce M , Siscovick, David , Newgard, Christopher , Herrington, David , Hoeschele, Ina , Shea, Steven , Stein, James H , Patel, Manesh , Post, Wendy , Jacobs, Jr, David , Parks, John S and Liu, Yongmei
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
BACKGROUNDPreclinical studies suggest that cholesterol accumulation leads to insulin resistance. We previously reported that alterations in a monocyte cholesterol metabolism transcriptional network (CMTN) - suggestive of cellular cholesterol accumulation - were cross-sectionally associated with obesity and type 2 diabetes (T2D). Here, we sought to...
Alternative Titles
Full title
LXR signaling pathways link cholesterol metabolism with risk for prediabetes and diabetes
Authors, Artists and Contributors
Author / Creator
Nguyen, Anh Tram
Lohman, Kurt
Hensley, Michael T
Parker, Daniel
Hou, Li
Taylor, Jackson
Voora, Deepak
Sawyer, Janet K
Boudyguina, Elena
Bancks, Michael P
Bertoni, Alain
Pankow, James S
Rotter, Jerome I
Goodarzi, Mark O
Tracy, Russell P
Murdoch, David M
Rich, Stephen S
Psaty, Bruce M
Siscovick, David
Newgard, Christopher
Herrington, David
Hoeschele, Ina
Shea, Steven
Stein, James H
Patel, Manesh
Post, Wendy
Jacobs, Jr, David
Parks, John S
Liu, Yongmei
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11093600
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11093600
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI173278
