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HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105007

HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

About this item

Full title

HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2020-10, Vol.77 (19), p.3797-3821

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

HOX genes encode a family of evolutionarily conserved homeodomain transcription factors that are crucial both during development and adult life. In humans, 39 HOX genes are arranged in four clusters (HOXA, B, C, and D) in chromosomes 7, 17, 12, and 2, respectively. During embryonic development, particular epigenetic states accompany their expressio...

Alternative Titles

Full title

HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105007

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105007

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-020-03508-9

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