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Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105752

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

About this item

Full title

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

Publisher

Cham: Springer International Publishing

Journal title

Cellular and molecular life sciences : CMLS, 2018-11, Vol.75 (21), p.4021-4040

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Mitochondrial intracrines are extracellular signaling proteins, targeted to the mitochondria. The pathway for mitochondrial targeting of mitochondrial intracrines and actions in the mitochondria remains unknown. Megalin/LRP2 mediates the uptake of vitamins and proteins, and is critical for clearance of amyloid-β protein from the brain. Megalin muta...

Alternative Titles

Full title

Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105752

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11105752

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-018-2847-3

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