Log in to save to my catalogue

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacolog...

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacolog...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11113908

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

About this item

Full title

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

Publisher

Basel: Springer Basel

Journal title

Cellular and molecular life sciences : CMLS, 2014-08, Vol.71 (16), p.3173-3185

Language

English

Formats

Publication information

Publisher

Basel: Springer Basel

More information

Scope and Contents

Contents

It has been proposed that dual inhibitors of protein kinases CK2 and PIM-1 are tools particularly valuable to induce apoptosis of cancer cells, a property, however, implying cell permeability, which is lacking in the case of selective CK2/PIM-1 inhibitors developed so far. To fill this gap, we have derivatized the scaffold of the promiscuous CK2 in...

Alternative Titles

Full title

Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potential

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11113908

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11113908

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-013-1552-5

How to access this item