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PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and infl...

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and infl...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11114032

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

About this item

Full title

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

Publisher

Basel: Springer Basel

Journal title

Cellular and molecular life sciences : CMLS, 2015-11, Vol.72 (22), p.4383-4397

Language

English

Formats

Publication information

Publisher

Basel: Springer Basel

More information

Scope and Contents

Contents

Internal ribosomal entry site (IRES)-mediated translation initiation is constitutively activated during stress conditions such as tumorigenesis and hypoxia. The RNA editing enzyme ADAR1 plays an important role in physiology and pathology. Initially, we found that the
ADAR1
p150
or
p110
transcript levels were decreased in glioma cells...

Alternative Titles

Full title

PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11114032

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11114032

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-015-1938-7

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