PPAR γ partial agonist, KR-62776, inhibits adipocyte differentiation via activation of ERK
PPAR γ partial agonist, KR-62776, inhibits adipocyte differentiation via activation of ERK
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Author / Creator
Kim, J , Han, D. C , Kim, J. M , Lee, S. Y , Kim, S. J , Woo, J. R , Lee, J. W , Jung, S.-K , Yoon, K. S , Cheon, H. G , Kim, S. S , Hong, S. H and Kwon, B.-M
Publisher
Basel: Basel : Birkhäuser-Verlag
Journal title
Language
English
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Basel: Basel : Birkhäuser-Verlag
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Contents
Indenone KR-62776 acts as an agonist of PPARγ without inducing obesity in animal models and cells. X-ray crystallography reveals that the indenone occupies the binding pocket in a different manner than rosiglitazone. 2-Dimensional gel-electrophoresis showed that the expression of 42 proteins was altered more than 2.0-fold between KR-62776- or rosig...
Alternative Titles
Full title
PPAR γ partial agonist, KR-62776, inhibits adipocyte differentiation via activation of ERK
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11115545
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11115545
Other Identifiers
ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-009-9169-4
