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Triosephosphate isomerase: a highly evolved biocatalyst

Triosephosphate isomerase: a highly evolved biocatalyst

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11115733

Triosephosphate isomerase: a highly evolved biocatalyst

About this item

Full title

Triosephosphate isomerase: a highly evolved biocatalyst

Publisher

Basel: Basel : SP Birkhäuser Verlag Basel

Journal title

Cellular and molecular life sciences : CMLS, 2010-12, Vol.67 (23), p.3961-3982

Language

English

Formats

Publication information

Publisher

Basel: Basel : SP Birkhäuser Verlag Basel

More information

Scope and Contents

Contents

Triosephosphate isomerase (TIM) is a perfectly evolved enzyme which very fast interconverts dihydroxyacetone phosphate and d-glyceraldehyde-3-phosphate. Its catalytic site is at the dimer interface, but the four catalytic residues, Asn11, Lys13, His95 and Glu167, are from the same subunit. Glu167 is the catalytic base. An important feature of the T...

Alternative Titles

Full title

Triosephosphate isomerase: a highly evolved biocatalyst

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11115733

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11115733

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-010-0473-9

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