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Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various...

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11147118

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

About this item

Full title

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

Publisher

Switzerland: Springer Nature B.V

Journal title

Cellular and molecular life sciences : CMLS, 2000-05, Vol.57 (5), p.738-746

Language

English

Formats

Publication information

Publisher

Switzerland: Springer Nature B.V

More information

Scope and Contents

Contents

The human aging process is associated with vascular endothelial dysfunction. However, humoral factors which might protect against endothelial dysfunction during aging have not yet been identified. We recently identified the klotho gene as a possible regulator of human aging. In the present study using the klotho-deficient heterozygous mouse, we exa...

Alternative Titles

Full title

Endothelial dysfunction in the klotho mouse and downregulation of klotho gene expression in various animal models of vascular and metabolic diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11147118

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11147118

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s000180050038

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