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α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial streng...

α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial streng...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11151094

α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration

About this item

Full title

α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration

Publisher

United States: The American Society for Cell Biology

Journal title

Molecular biology of the cell, 2024-05, Vol.35 (5), p.ar65

Language

English

Formats

Publication information

Publisher

United States: The American Society for Cell Biology

More information

Scope and Contents

Contents

α-catenin (α-cat) displays force-dependent unfolding and binding to actin filaments through direct and indirect means, but features of adherens junction structure and function most vulnerable to loss of these allosteric mechanisms have not been directly compared. By reconstituting an α-cat F-actin-binding domain unfolding mutant known to exhibit en...

Alternative Titles

Full title

α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11151094

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11151094

Other Identifiers

ISSN

1059-1524,1939-4586

E-ISSN

1939-4586

DOI

10.1091/mbc.E23-01-0036

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