Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness
Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Language
English
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Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Contents
The membrane‐anchored metalloproteinase tumor necrosis factor‐α‐converting enzyme (TACE/a disintegrin and metalloproteinase [ADAM] 17) is key in proteolytic ectodomain shedding of several membrane‐bound growth factors, cytokines and receptors. The expression and activity of ADAM17 increases under some pathological conditions including stroke, and p...
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Full title
Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158419
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158419
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ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2007.00440.x