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Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158419

Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

About this item

Full title

Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

Publisher

Melbourne, Australia: Blackwell Publishing Asia

Journal title

Cancer science, 2007-05, Vol.98 (5), p.674-684

Language

English

Formats

Publication information

Publisher

Melbourne, Australia: Blackwell Publishing Asia

More information

Scope and Contents

Contents

The membrane‐anchored metalloproteinase tumor necrosis factor‐α‐converting enzyme (TACE/a disintegrin and metalloproteinase [ADAM] 17) is key in proteolytic ectodomain shedding of several membrane‐bound growth factors, cytokines and receptors. The expression and activity of ADAM17 increases under some pathological conditions including stroke, and p...

Alternative Titles

Full title

Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158419

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158419

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2007.00440.x

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