Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib‐resistant gastr...
Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib‐resistant gastrointestinal stromal tumor
About this item
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Author / Creator
Publisher
Melbourne, Australia: Blackwell Publishing Asia
Journal title
Language
English
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Publication information
Publisher
Melbourne, Australia: Blackwell Publishing Asia
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Scope and Contents
Contents
Although imatinib showed high activity for advanced gastrointestinal stromal tumor (GIST) and improved the prognosis of GIST patients, resistance to the drug appears with prolonged use. Mechanisms of acquired resistance are still under investigation. In the present study, we carried out histologic and genetic analysis of 45 secondary resistant lesi...
Alternative Titles
Full title
Secondary mutations in the kinase domain of the KIT gene are predominant in imatinib‐resistant gastrointestinal stromal tumor
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158696
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11158696
Other Identifiers
ISSN
1347-9032,1349-7006
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2008.00727.x
