Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers
Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers
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Oxford, UK: Blackwell Publishing Ltd
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Language
English
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Publisher
Oxford, UK: Blackwell Publishing Ltd
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Contents
The SFRP1 gene on chromosome 8p11.2 encodes a Wnt signaling antagonist, and was recently demonstrated to be a new tumor suppressor that is inactivated by promoter methylation in human colon cancers. Here, we analyzed promoter methylation of the SFRP1 gene in human ovarian cancers, in which loss of heterozygosity in 8p is frequently observed and inv...
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Full title
Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160044
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160044
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ISSN
1347-9032
E-ISSN
1349-7006
DOI
10.1111/j.1349-7006.2004.tb03255.x