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Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160044

Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

About this item

Full title

Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

Cancer science, 2004-09, Vol.95 (9), p.741-744

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

The SFRP1 gene on chromosome 8p11.2 encodes a Wnt signaling antagonist, and was recently demonstrated to be a new tumor suppressor that is inactivated by promoter methylation in human colon cancers. Here, we analyzed promoter methylation of the SFRP1 gene in human ovarian cancers, in which loss of heterozygosity in 8p is frequently observed and inv...

Alternative Titles

Full title

Methylation‐associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160044

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11160044

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2004.tb03255.x

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