A disease-associated gene desert directs macrophage inflammation through ETS2
A disease-associated gene desert directs macrophage inflammation through ETS2
About this item
Full title
Author / Creator
Stankey, C. T. , Bourges, C. , Haag, L. M. , Turner-Stokes, T. , Piedade, A. P. , Palmer-Jones, C. , Papa, I. , Silva dos Santos, M. , Zhang, Q. , Cameron, A. J. , Legrini, A. , Zhang, T. , Wood, C. S. , New, F. N. , Randzavola, L. O. , Speidel, L. , Brown, A. C. , Hall, A. , Saffioti, F. , Parkes, E. C. , Edwards, W. , Direskeneli, H. , Grayson, P. C. , Jiang, L. , Merkel, P. A. , Saruhan-Direskeneli, G. , Sawalha, A. H. , Tombetti, E. , Quaglia, A. , Thorburn, D. , Knight, J. C. , Rochford, A. P. , Murray, C. D. , Divakar, P. , Green, M. , Nye, E. , MacRae, J. I. , Jamieson, N. B. , Skoglund, P. , Cader, M. Z. , Wallace, C. , Thomas, D. C. and Lee, J. C.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Increasing rates of autoimmune and inflammatory disease present a burgeoning threat to human health
1
. This is compounded by the limited efficacy of available treatments
1
and high failure rates during drug development
2
, highlighting an urgent need to better understand disease mechanisms. Here we show how functional genomics co...
Alternative Titles
Full title
A disease-associated gene desert directs macrophage inflammation through ETS2
Authors, Artists and Contributors
Author / Creator
Bourges, C.
Haag, L. M.
Turner-Stokes, T.
Piedade, A. P.
Palmer-Jones, C.
Papa, I.
Silva dos Santos, M.
Zhang, Q.
Cameron, A. J.
Legrini, A.
Zhang, T.
Wood, C. S.
New, F. N.
Randzavola, L. O.
Speidel, L.
Brown, A. C.
Hall, A.
Saffioti, F.
Parkes, E. C.
Edwards, W.
Direskeneli, H.
Grayson, P. C.
Jiang, L.
Merkel, P. A.
Saruhan-Direskeneli, G.
Sawalha, A. H.
Tombetti, E.
Quaglia, A.
Thorburn, D.
Knight, J. C.
Rochford, A. P.
Murray, C. D.
Divakar, P.
Green, M.
Nye, E.
MacRae, J. I.
Jamieson, N. B.
Skoglund, P.
Cader, M. Z.
Wallace, C.
Thomas, D. C.
Lee, J. C.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11168933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11168933
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-024-07501-1