Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arth...
Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response
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Author / Creator
Corsiero, Elisa , Caliste, Mattia , Jagemann, Lucas , Fossati-Jimack, Liliane , Goldmann, Katriona , Cubuk, Cankut , Ghirardi, Giulia M. , Prediletto, Edoardo , Rivellese, Felice , Alessandri, Cristiano , Hopkinson, Mark , Javaheri, Behzad , Pitsillides, Andrew A. , Lewis, Myles J. , Pitzalis, Costantino and Bombardieri, Michele
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Ectopic lymphoid structures (ELSs) in the rheumatoid synovial joints sustain autoreactivity against locally expressed autoantigens. We recently identified recombinant monoclonal antibodies (RA-rmAbs) derived from single, locally differentiated rheumatoid arthritis (RA) synovial B cells, which specifically recognize fibroblast-like synoviocytes (FLS...
Alternative Titles
Full title
Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178537
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178537
Other Identifiers
ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI169754
