RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose
RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose
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Publisher
United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Glucose plays a key role in shaping pancreatic β cell function. Thus, deciphering the mechanisms by which this nutrient stimulates β cells holds therapeutic promise for combating β cell failure in type 2 diabetes (T2D). β Cells respond to hyperglycemia in part by rewiring their mRNA metabolism, yet the mechanisms governing these changes remain poor...
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Full title
RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178539
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178539
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ISSN
1558-8238,0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI172436