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RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose

RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178539

RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose

About this item

Full title

RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2024-06, Vol.134 (12)

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Glucose plays a key role in shaping pancreatic β cell function. Thus, deciphering the mechanisms by which this nutrient stimulates β cells holds therapeutic promise for combating β cell failure in type 2 diabetes (T2D). β Cells respond to hyperglycemia in part by rewiring their mRNA metabolism, yet the mechanisms governing these changes remain poor...

Alternative Titles

Full title

RNA-binding protein PCBP2 regulates pancreatic β cell function and adaptation to glucose

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178539

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11178539

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI172436

How to access this item