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Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in m...

Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11180854

Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease

About this item

Full title

Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease

Publisher

United States: John Wiley and Sons Inc

Journal title

Alzheimer's & dementia, 2024-06, Vol.20 (6), p.3987-4001

Language

English

Formats

Publication information

Publisher

United States: John Wiley and Sons Inc

More information

Scope and Contents

Contents

INTRODUCTION
Increasing evidence suggests that metabolic impairments contribute to early Alzheimer's disease (AD) mechanisms and subsequent dementia. Signals in metabolic pathways conserved across species can facilitate translation.
METHODS
We investigated differences in serum and brain metabolites between the early‐onset 5XFAD and late‐on...

Alternative Titles

Full title

Metabolomics profiling reveals distinct, sex‐specific signatures in serum and brain metabolomes in mouse models of Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11180854

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11180854

Other Identifiers

ISSN

1552-5260,1552-5279

E-ISSN

1552-5279

DOI

10.1002/alz.13851

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