Measuring the Efficiency of Purging by non-random Mating in Human Populations
Measuring the Efficiency of Purging by non-random Mating in Human Populations
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Publisher
UK: Oxford University Press
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Language
English
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Publisher
UK: Oxford University Press
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Abstract
Human populations harbor a high concentration of deleterious genetic variants. Here, we tested the hypothesis that non-random mating practices affect the distribution of these variants, through exposure in the homozygous state, leading to their purging from the population gene pool. To do so, we produced whole-genome sequencing data for...
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Full title
Measuring the Efficiency of Purging by non-random Mating in Human Populations
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11184347
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11184347
Other Identifiers
ISSN
0737-4038,1537-1719
E-ISSN
1537-1719
DOI
10.1093/molbev/msae094
