Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in e...
Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer’s Disease
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Early and progressive dysfunctions of the dopaminergic system from the Ventral Tegmental Area (VTA) have been described in Alzheimer’s Disease (AD). During the long pre-symptomatic phase, alterations in the function of Parvalbumin interneurons (PV-INs) are also observed, resulting in cortical hyperexcitability represented by subclinical epilepsy an...
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Dopamine neuron degeneration in the Ventral Tegmental Area causes hippocampal hyperexcitability in experimental Alzheimer’s Disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11189820
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11189820
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ISSN
1359-4184,1476-5578
E-ISSN
1476-5578
DOI
10.1038/s41380-024-02408-9
