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Identification of RFC4 as a potential biomarker for pan‐cancer involving prognosis, tumour immune mi...

Identification of RFC4 as a potential biomarker for pan‐cancer involving prognosis, tumour immune mi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11190950

Identification of RFC4 as a potential biomarker for pan‐cancer involving prognosis, tumour immune microenvironment and drugs

About this item

Full title

Identification of RFC4 as a potential biomarker for pan‐cancer involving prognosis, tumour immune microenvironment and drugs

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2024-06, Vol.28 (12), p.e18478-n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

RFC4 is required for DNA polymerase δ and DNA polymerase ε to initiate DNA template expansion. Downregulated RFC4 inhibits tumour proliferation by causing S‐phase arrest and inhibiting mitosis, resulting in the reduction of tumour cells. RFC4 has been implicated that it plays an important role in the initiation and progression of cancers, but a com...

Alternative Titles

Full title

Identification of RFC4 as a potential biomarker for pan‐cancer involving prognosis, tumour immune microenvironment and drugs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11190950

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11190950

Other Identifiers

ISSN

1582-1838,1582-4934

E-ISSN

1582-4934

DOI

10.1111/jcmm.18478

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