Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma
Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Mutations affecting codon 172 of the isocitrate dehydrogenase 2 (IDH2) gene define a subgroup of sinonasal undifferentiated carcinomas (SNUCs) with a relatively favorable prognosis and a globally hypermethylated phenotype. They are also recurrent (along with IDH1 mutations) in gliomas, acute myeloid leukemia, and intrahepatic cholangiocarcinoma. Co...
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Methylation-Based Characterization of a New IDH2 Mutation in Sinonasal Undifferentiated Carcinoma
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11204065
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11204065
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms25126518