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Itga5-PTEN signaling regulates striatal synaptic strength and motor coordination in Parkinson's dise...

Itga5-PTEN signaling regulates striatal synaptic strength and motor coordination in Parkinson's dise...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11234218

Itga5-PTEN signaling regulates striatal synaptic strength and motor coordination in Parkinson's disease

About this item

Full title

Itga5-PTEN signaling regulates striatal synaptic strength and motor coordination in Parkinson's disease

Publisher

Australia: Ivyspring International Publisher

Journal title

International journal of biological sciences, 2024-01, Vol.20 (9), p.3302-3316

Language

English

Formats

Publication information

Publisher

Australia: Ivyspring International Publisher

More information

Scope and Contents

Contents

: Parkinson's disease (PD) is marked by the loss of dopaminergic neurons in the substantia nigra pars compacta, leading to motor and cognitive dysfunctions. The molecular mechanisms underlying synaptic alterations in PD remain elusive, with a focus on the role of Itga5 in synaptic integrity and motor coordination and TAT-Itga5 was designed to suppr...

Alternative Titles

Full title

Itga5-PTEN signaling regulates striatal synaptic strength and motor coordination in Parkinson's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11234218

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11234218

Other Identifiers

ISSN

1449-2288

E-ISSN

1449-2288

DOI

10.7150/ijbs.96116

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